South Korean scientists have identified a potentially promising new pathway for treating ischemic stroke, long considered one of the most difficult challenges in modern medicine.
According to the South Korean team, doctors in China are interested in a partnership and learning more about an experimental drug that it has developed to combat the disease.
The team’s study, titled “Oxidative stress-induced astrocytic collagen biosynthesis drives glial barrier formation and neuronal death in ischemic stroke,” was published online last week in the journal Cell Metabolism.
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Ischemic stroke occurs when a blood clot or other blockage obstructs a cerebral blood vessel, cutting off oxygen and nutrients and causing brain cells to die.
More than 100,000 patients are diagnosed each year in South Korea, which has a population of about 52 million.
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Survivors often suffer severe aftereffects, including motor disabilities and cognitive decline. Treatment is further complicated by a narrow three-hour “golden time” window after symptom onset, during which patients must receive emergency care.